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Unstable Personality Disorder | Herbal Dispatch Canada

Emotionally Unstable Personality Disorder (EUPD), also referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional stability, and may result in impulsive or self-harm behaviors. The financial burden of treatment can be significant, with success rates between 35% and 50%. Researchers are investigating alternative therapies to supplement traditional methods at Herbal Dispatch Canada.

A notable potential addition to EUPD treatment is cannabis, commonly known as weed. It is a cost-effective option, and its components can provide benefits to those suffering from EUPD. Individuals unable to afford extensive treatments might seek out cannabis deals online for more affordable choices.

Key Takeaways:

  • Participants with EUPD using THC or high CBD report positive outcomes in symptom management.
  • High doses of CBD (800 mg/day) and THC flower treatment can elevate circulating levels of anandamide.
  • Dysfunction within the endocannabinoid system, which regulates emotions and stress, is implicated in Emotionally Unstable Personality Disorder.

Emotionally Unstable Personality Disorder or Borderline Personality Disorder

EUPD is a mental health challenge that alters self-perception and interpersonal relationships, resulting in daily life complications. It is characterized by intense, unstable relationships, impulsivity, and a distorted self-image.

While the precise causes remain uncertain, factors like genetics, trauma, and neurotransmitter imbalances may contribute. Dysfunction in the endocannabinoid system, which manages emotion and stress, could exacerbate EUPD symptoms.

EUPD Treatment

Despite guidelines indicating that no medications are effective for EUPD, clinicians may prescribe drugs such as antipsychotics and antidepressants.

Antipsychotic and sedative medications may provide short-term crisis management or support for coexisting conditions. A significant proportion of EUPD patients—up to 90% in some studies—use at least one psychotropic medication, including antipsychotics, antidepressants, mood stabilizers, and sedatives.

Polypharmacy is prevalent among these patients. Most medications carry side effects and are often used off-label for EUPD. While some drugs might alleviate specific symptoms, they do not alter the overall prognosis of the disorder.

Cannabis-Based Medicine for EUPD (CBM)

Cannabis-based medicines are derived from the cannabis plant and contain cannabinoids, the active compounds such as tetrahydrocannabinol (THC) and cannabidiol (CBD). These products address medical conditions and symptoms, including pain, inflammation, anxiety, and seizures.

Numerous studies are currently exploring mental health impacts. For instance, research in Frontiers in Psychiatry suggests that marijuana can enhance depression and improve sleep quality and overall quality of life. These findings advocate for further investigation into marijuana’s effects on various mental health disorders.

CBM for Unstable Personality Disorder

A narrative review and case study in 2022 examined the use of cannabinoids in alleviating EUPD symptoms for seven patients. Researchers assessed cellular mechanisms and reviewed existing evidence for cannabis-based medicinal products (CBMP) as a potential therapeutic option for EUPD.

Materials and Methods

ParticipantsDiagnosed with EUPD who had tried at least one medication and one form of psychotherapyAt least one follow-up review at a Zerenia clinic, with patient-reported outcome measures (PROMS) records.
CBM UsedDried Flower for inhalation (20-60g per month)Oral Extracts with THC (9-10mg/day), and CBD (40mg/day).Formulation: Chemotype 1: High THC, low CBD. Chemotype 2: Balanced THC and CBD. Chemotype 3: High CBD, low THC.
MeasurementClinical Global Impression Improvement (CGI-I) Scale: A 1-7 scale where 1 indicates “very much improved” and 7 indicates “very much worse.”Patient’s Global Impression of Change (PGIC) Scale: A 1-7 scale where 1 represents “no change or worse” and 7 signifies “a great deal better and a considerable improvement.”

Researchers personalized dosing through gradual titration and provided guidelines for increasing the dose until satisfactory symptom control was achieved or side effects were noted.

Results

After one month, six participants reported improvements, with five rating their change as a six on the PGIC scale. Only one patient, who received a chemotype 2 oral extract, did not experience benefits, suggesting that inhaled THC or higher oral CBD doses may be more effective.

All participants tolerated the treatment well, with no side effects reported, which is crucial for adherence. Younger individuals might feel more at ease with medical cannabis despite societal stigma.

Hypothesis

Researchers propose that exogenous cannabinoids could help restore the tonic activation of the endocannabinoid system (ECS) in the central nervous system (CNS). THC directly stimulates presynaptic CB1 receptors, and both cannabinoids interact with fatty-acid binding proteins (FABPs), which may hinder the deactivation of anandamide.

High doses of oral CBD (800 mg/day) and patients treated with chemotype 1 flower showed elevated levels of anandamide in circulation. It remains unclear whether this is due to CBD influencing anandamide transport or degradation or if it targets other molecular pathways. Conversely, psychiatric medications typically require 2-3 weeks for initial effects and longer for remission.

Rapid symptom relief can be crucial during an “EUPD crisis,” when distressed individuals may resort to benzodiazepines and other anxiety medications. However, these medications can induce rapid tolerance and dependency.

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Manage Changes in Behavior with Bulk Cannabis Via Mail-Order Marijuana Service

Cannabinoids effectively manage unstable personality disorders by targeting the ECS to sustain anandamide balance. Patients with EUPD can benefit from purchasing cannabis online or inexpensive products to assist in symptom management.

An online cannabis store offering same-day delivery or mail-order options provides a blend of quality and affordability. Experience exceptional customer service from a friendly team and discover a wide array of bulk cannabis strains, edibles, concentrates, and oils to enhance your experience. Buy cannabis online at Herbal Dispatch Canada.

Frequently Asked Questions

Does cheap marijuana have poor quality?

No, price is not the sole determinant of quality. You can evaluate quality by examining the product’s physical traits and personal experience. Some dispensaries may offer lower prices through monthly or clearance promotions. If a dispensary’s prices are significantly lower than the industry standard, it may raise quality concerns.

Does marijuana cause any adverse effects when managing BPD?

Participants in the study reported no adverse side effects from marijuana. This is crucial for medication adherence, as a review of 36 studies indicated that side effects accounted for 28% of patients’ non-adherence to antipsychotics. A negative perception of antipsychotic medication was the second most frequent reason for intentional non-adherence, at 30.5%.

What is the quickest way to experience the effects of cannabinoids for an EUPD problem?

Smoking, vaping, and dabbing are the fastest ways to feel the effects of cannabinoids. In the study, participants utilized vaping to consume dried flower. While smoking and vaping yield similar effects, the distinction lies in inhaling smoke (from smoking) versus vapor (from vaping). Dabbing, which involves using concentrates, also provides rapid onset of effects.

How many times can I smoke or vape to manage my symptoms?

The effectiveness of cannabis strains and products varies based on individual response. In the study, researchers permitted patients to adjust their daily dose (between 0.5 and 2 grams per day) as long as they did not exceed the monthly limit. For extracts, patients recorded their daily dosage.

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